Kaijser J, Sayasneh A, Van Hoorde K et al (2014) Presurgical diagnosis of adnexal tumours using mathematical models and scoring systems: a systematic review and meta-analysis. J Ultrasound Med 28:285–291Īmor F, Alcázar JL, Vaccaro H, León M, Iturra A (2011) GI-RADS reporting system for ultrasound evaluation of adnexal masses in clinical practice: a prospective multicenter study. BJOG 119:662–671Īmor F, Vaccaro H, Alcázar JL, León M, Craig JM, Martinez J (2009) Gynecologic imaging reporting and data system: a new proposal for classifying adnexal masses on the basis of sonographic findings. Van Calster B, Timmerman D, Valentin L et al (2012) Triaging women with ovarian masses for surgery: observational diagnostic study to compare RCOG guidelines with an International Ovarian Tumour Analysis (IOTA) group protocol. Van Calster B, Van Hoorde K, Valentin L et al (2014) Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and secondary metastatic tumours: prospective multicentre diagnostic study. Timmerman D, Van Calster B, Testa A et al (2016) Predicting the risk of malignancy in adnexal masses based on the Simple Rules from the International Ovarian Tumor Analysis group. Timmerman D, Testa AC, Bourne T et al (2008) Simple ultrasound-based rules for the diagnosis of ovarian cancer. Timmerman D, Valentin L, Bourne TH et al (2000) Terms, definitions and measurements to describe the sonographic features of adnexal tumors: a consensus opinion from the International Ovarian Tumor Analysis (IOTA) Group. Levine D, Brown DL, Andreotti RF et al (2010) Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of Radiologists in Ultrasound consensus conference statement. Liu J, Xu Y, Wang J (2007) Ultrasonography, computed tomography and magnetic resonance imaging for diagnosis of ovarian carcinoma. ACR appropriateness criteria 2008: clinically suspected adnexal mass. The O-RADS, GI-RADS, and IOTA showed similar overall inter-reviewer agreement (IRA) (κ = 0.77, 0.69, and 0.63, respectively), with a tendency toward higher IRA with O-RADS than with GI-RADS and IOTA.Īmerican College of Radiology.The O-RADS had significantly higher sensitivity for malignancy than GI-RADS and IOTA (96.8% vs 92.7% and 92.1% p = 0.003 and 0.0007, respectively), but non-significant slightly lower specificity (92.8% vs 93.6% and 93.2%, respectively p > 0.05).The malignancy rates were comparable to recommended rates by previous literature in O-RADS and IOTA, but higher in GI-RADS.O-RADS had higher sensitivity than GI-RADS and IOTA simple rules with relatively similar specificity and reliability. O-RADS compares favorably with GI-RADS and IOTA. O-RADS, GI-RADS, and IOTA showed similar overall IRA ( κ = 0.77, 0.69, and 0.63, respectively) with a tendency toward higher IRA with O-RADS than with GI-RADS and IOTA. O-RADS had significantly higher sensitivity for malignancy than GI-RAD and IOTA ( p = 0.003 and 0.0007, respectively), but non-significant slightly lower specificity ( p > 0.05). Malignancy rates were comparable to recommended rates by previous literature in O-RADS and IOTA, but higher in GI-RADS. Of the 647 AM, 178 were malignant and 469 were benign. ResultsĪ total of 609 women (mean age, 48 ± 13.7 years range, 18–72 years) with 647 AM were included. Kappa statistics were used to assess the inter-reviewer agreement (IRA). Pathology and adequate follow-up were used as reference standards for calculating the validity of three US classification systems for diagnosis of AM. Five experienced consultant radiologists independently categorized each AM according to O-RADS, gynecologic imaging reporting and data system (GI-RADS), and international ovarian tumor analysis (IOTA) simple rules. This retrospective multicenter study between May 2016 and December 2019 assessed consecutive women with AM detected by the US. This study aimed to compare the O-RADS with two other well-established US classification systems for diagnosis of AM. The American College of Radiology (ACR) recently published the ovarian-adnexal reporting and data system (O-RADS) to provide guidelines to physicians who interpret ultrasound (US) examinations of adnexal masses (AM).
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